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I-Anti- human CHI3L1 Antibody, i-Monoclonal yomuntu
Imininingwane yomkhiqizo Ulwazi Olujwayelekile I-Chitinase-3-like protein 1 (CHI3L1) iyi-glycoprotein ebopha i-heparin eyimfihlo inkulumo yayo ehlotshaniswa nokufuduka kwamaseli emisipha ebushelelezi.I-CHI3L1 iboniswa emazingeni aphezulu kumasiko e-postconfluent nodular VSMC kanye namazinga aphansi kumasiko akhulayo angaphansi.I-CHI3L1 iyi-lectin enethishu ekhawulelwe, ebopha i-chitin futhi iyilungu lomndeni we-glycosyl hydrolase 18. Ngokungafani nezinye izimpawu eziningi ze-monocyto / macrophage, isisho sayo sithi abs... -
Anti-human Her2 Antibody, Igundane Monoclonal
Imininingwane yomkhiqizo Ulwazi Olujwayelekile I-Human epidermal growth factor receptor 2 (HER2), eyaziwa nangokuthi i-ErbB2, NEU, ne-CD340, iwuhlobo I-membrane glycoprotein futhi iyingxenye yomndeni wama-epidermal growth factor (EGF).Iphrotheni ye-HER2 ayikwazi ukubopha izici zokukhula ngenxa yokushoda kwesizinda esibophezelayo se-ligand esaso futhi esivinjelwe ngokuzenzakalelayo.Kodwa-ke, i-HER2 yakha i-heterodimer namanye amalungu omndeni we-EGF receptor eboshwe nge-ligand, ngakho-ke iqinisa ukubopha kwe-ligand futhi ithuthukise i-kinase-med... -
Anti-human PGI Antibody, Igundane Monoclonal
Imininingwane yomkhiqizo Ulwazi Olujwayelekile I-Pepsinogen I, izandulela ze-pepsin, ikhiqizwa ulwelwesi lwesisu bese ikhishelwa kulume lwesisu kanye nokujikeleza kwe-peripheral.I-Pepsinogen iqukethe iketango elilodwa le-polypeptide lama-amino acid angama-375 anesilinganiso sesisindo samangqamuzana angama-42 kD.I-PG I (isoenzyme 1-5) ikhiqizwa ikakhulukazi amaseli ayinhloko ku-fundac mucosa, kuyilapho i-PG II (isoenzyme 6-7) ikhishwa yizindlala ze-pyloric kanye ne-proximal duodenal mucosa.Isandulela sibonisa izinombolo ze-stomac... -
Anti-human PG II Antibody, Igundane Monoclonal
Imininingwane yomkhiqizo Ulwazi Olujwayelekile I-Pepsinogen iwuhlobo lwe-pepsin futhi ikhiqizwa amaseli ayinhloko esiswini.Ingxenye enkulu ye-pepsinogen ikhishwa ku-lumen yesisu kodwa inani elincane lingatholakala egazini.Izinguquko ekugxilweni kwe-serum pepsinogen zitholwe ngezifo ze-Helicobacter pylori (H. Pylori), isifo se-peptic ulcer, i-gastritis, nomdlavuza wesisu.Ukuhlaziya okunembe kakhudlwana kungase kufinyelelwe ngokulinganisa isilinganiso se-pepsinogen I/II.Izakhiwo Zibhanqa kabusha... -
Anti- human PIVKA -II Antibody, Igundane Monoclonal
Imininingwane yomkhiqizo Ulwazi Olujwayelekile Iphrotheni Ebangelwa Ukungabi Nakho Kwe-Vitamin K noma I-Antagonist-II (PIVKA-II), eyaziwa nangokuthi i-Des-γ-carboxy-prothrombin (DCP), iwuhlobo olungavamile lwe-prothrombin.Ngokuvamile, izinsalela ze-prothrombin eziyi-10 ze-glutamic acid (Glu) kusizinda se-γ-carboxyglutamic acid (Gla) ezikhundleni 6, 7, 14, 16, 19, 20,25, 26, 29 kanye ne-32 zingu-γ-carboxylated ku-Glasi ngevithamini. -K encike ku-γ- glutamyl carboxylase esibindini bese ikhishelwa ku-plasma.Ezigulini ezine-hepatocellular carcinom... -
I-Anti- human s100 β Antibody, Igundane I-Monoclonal
Imininingwane yomkhiqizo Ulwazi Olujwayelekile I-S100B iphrotheni ebopha i-calcium, ekhishwa kuma-astrocyte.Iphrotheni encane ye-dimeric cytosolic (21 kDa) ehlanganisa i-ββ noma i-αβ chain.I-S100B ibandakanyeka ezinhlobonhlobo zemisebenzi yokulawula engaphakathi kweseli nengaphandle kwamaseli.Kule minyaka eyishumi edlule, i-S100B iye yavela njenge-peripheral biomarker yomonakalo we-blood-brain barrier (BBB) kanye nokulimala kwe-CNS.Amazinga aphakanyisiwe we-S100B akhombisa ngokunembile ubukhona bezimo ze-neuropathological kuhlanganisa... -
I-anti- human TIMP1 Antibody, Igundane i-Monoclonal
Imininingwane yomkhiqizo Ulwazi Olujwayelekile I-TIMP metallopeptidase inhibitor 1, eyaziwa nangokuthi i-TIMP-1/TIMP1, i-Collagenase inhibitor 16C8 fibroblast Umsebenzi we-Erythroid-potentiating, i-TPA-S1TPA-induced proteinTissue inhibitor of metalloproteinases 1, i-metalloproteinase yemvelo ye-MloMP iqembu lama-peptidase elihilelekile ekucekeleni phansi kwe-matrix engaphandle kwamaseli.I-TIMP-1/TIMP1 itholakala kuzicubu zengane nezabantu abadala.Amazinga aphezulu kakhulu atholakala emathanjeni, emaphashini, e-ovary nasesibelethweni.Izinkinga nge... -
I-Anti-Human MPO Antibody, Igundane I-Monoclonal
Imininingwane yomkhiqizo Ulwazi Olujwayelekile MPO (i-myeloperoxidase) iyi-enzyme ye-peroxidase ekhiqizwe ama-leukocyte adlala indima ye-pathogenic esifweni senhliziyo nemithambo yegazi, ikakhulukazi ngokuqalisa ukungasebenzi kahle kwe-endothelial.I-Myeloperoxidase (MPO) iyi-enzyme ebalulekile, engenye yezingxenye zesistimu ye-antibacterial kuma-neutrophils nama-monocyte.I-MPO ibamba iqhaza ekuphenduleni ukuvuvukala ezindaweni eziningi emzimbeni, kuhlanganise nezindlala zebele.I-Myeloperoxidase (MPO), ingxenye ethile... -
I-anti-human GDF15 Antibody, Igundane I-Monoclonal
Imininingwane yomkhiqizo Ulwazi Olujwayelekile Lokukhula-umehluko factor 15 (GDF15), eyaziwa nangokuthi i-MIC-1, iyilungu eliyimfihlo le-transforming growth factor (TGF) -β superfamily, njengenoveli yokulawula i-antihypertrophic factor enhliziyweni.I-GDF-15 / GDF15 ayivezwa enhliziyweni yomuntu omdala evamile kodwa yenziwa ngokuphendula izimo ezikhuthaza i-hypertrophy kanye ne-dilated cardiomyopathy futhi ivezwa kakhulu esibindini.I-GDF-15 / GDF15 inendima ekulawuleni indlela yokuvuvukala kanye ne-apoptotic... -
I-anti- human Lp-PLA2 Antibody, Igundane Monoclonal
Imininingwane yomkhiqizo Ulwazi Olujwayelekile I-phospholipase A2 (Lp-PLA2) ehlotshaniswa ne-Lipoprotein (Lp-PLA2) ikhiqizwa amaseli avuvukalayo futhi ijikeleze ngokuyinhloko iboshwe ku-low-density lipoprotein (LDL) futhi ngokwezinga elincane ihlotshaniswa ne-high-density lipoprotein (HDL) ku-plasma yomuntu.I-LDL oxidation yaziwa njengesenzakalo sokuqala esiyinhloko ku-pathogenesis ye-atherosclerosis.Amazinga aphezulu e-Lp-PLA2 atholakale kuma-atherosclerotic plaque kanye nezilonda zokuphuka.Izincomo Zokubhangqa Kwezakhiwo I-CLIA (Capture-De... -
Anti-human GH Antibody, Igundane Monoclonal
Imininingwane yomkhiqizo Ihomoni Yokukhula Kolwazi Olujwayelekile (GH) noma i-somatotropin, eyaziwa nangokuthi i-hormone yokukhula komuntu (hGH noma i-HGH), iyihomoni ye-peptide ekhuthaza ukukhula, ukukhiqizwa kwamangqamuzana, nokuvuselelwa kwamaseli kubantu nakwezinye izilwane.Ngakho ibalulekile ekuthuthukisweni komuntu.I-GH iphinde ikhuthaze ukukhiqizwa kwe-IGF-1 futhi ikhulise ukugxila kweglucose kanye nama-fatty acids mahhala.Iwuhlobo lwe-mitogen oluqondene kuphela nama-receptors ezinhlotsheni ezithile zamaseli.I-GH iyi-191-amino acid, ... -
Anti-human PRL Antibody, Igundane Monoclonal
Imininingwane yomkhiqizo Ulwazi Olujwayelekile I-Prolactin (PRL), eyaziwa nangokuthi i-lactotropin, iyihomoni eyenziwe yindlala ye-pituitary, indlala encane engaphansi kobuchopho.I-Prolactin ibangela ukuthi amabele akhule futhi enze ubisi ngesikhathi sokukhulelwa nangemva kokuzalwa.Amazinga e-prolactin ngokuvamile aphezulu kwabesifazane abakhulelwe nomama abasha.Amazinga avamise ukuba aphansi kwabesifazane abangakhulelwe nakwabesilisa.Ukuhlolwa kwamazinga eprolactin kuvame ukusetshenziselwa: ★ Ukuthola i-prolactinoma (uhlobo lwesimila se-pituitary gland) ★ Usizo...
