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I-Anti-Human SHBG Antibody, Igundane Monoclonal
Imininingwane yomkhiqizo Ulwazi Olujwayelekile Ihomoni ebopha i-globulin yocansi (SHBG) iyi-glycoprotein engaba ngu-80-100 kDa;inobudlelwane obuphezulu be-17 beta-hydroxysteroid hormones njenge-testosterone ne-estradiol.Ukugxila kwe-SHBG ku-plasma kulawulwa, phakathi kwezinye izinto, ibhalansi ye-androgen/estrogen, amahomoni egilo, i-insulin kanye nezici zokudla.Kuyiprotheni yokuthutha ebaluleke kakhulu yama-estrogens nama-androgens egazini le-peripheral.Ukugxila kwe-SHBG kuyisici esikhulu esilawula ukungazi kwabo ... -
Anti-human calprotectin Antibody, Igundane Monoclonal
Imininingwane yomkhiqizo Ulwazi Olujwayelekile I-Calprotectin iphrotheni ekhishwa uhlobo lwengqamuzana elimhlophe legazi elibizwa ngokuthi i-neutrophil.Uma kukhona ukuvuvukala emgudwini wesisu (GI), ama-neutrophil athuthela endaweni futhi akhulule i-calprotectin, okuholela ekukhuphukeni kwezinga esitulweni.Ukulinganisa izinga le-calprotectin esitulweni kuyindlela ewusizo yokuthola ukuvuvukala emathunjini.Ukuvuvukala kwamathumbu kuhlotshaniswa nesifo samathumbu esivuvukalayo (IBD) kanye nokunye okungenwa yi-bacterial GI... -
I-IL6 ye-anti-human, i-Mouse Monoclonal
Imininingwane yomkhiqizo Ulwazi Olujwayelekile I-Interleukin-6 (IL-6) iyi-cytokine ye-α-helical enemisebenzi eminingi elawula ukukhula kwamangqamuzana nokuhlukaniswa kwezicubu ezihlukahlukene, eyaziwa ikakhulukazi ngendima yayo ekuphenduleni kokuzivikela komzimba kanye nokusabela kwesigaba esibucayi.Iphrotheni ye-IL-6 ikhiqizwa izinhlobo ezahlukene zamaseli okuhlanganisa amaseli e-T nama-macrophage njenge-molecule ye-phosphorylated ne-glycosylated eguquguqukayo.Isebenzisa isenzo ngesamukeli sayo se-heterodimeric esakhiwe i-IL-6R engenayo i-tyrosine/kinas... -
Anti-human MMP-3 Antibody, Igundane Monoclonal
Imininingwane yomkhiqizo Ulwazi Olujwayelekile I-Matrix metallopeptidase 3 (efushanisiwe njenge-MMP3) yaziwa nangokuthi i-stromelysin 1 ne-progelatinase.I-MMP3 iyilungu lomndeni we-matrix metalloproteinase (MMP) amalungu awo abambe iqhaza ekuqhekekeni kwe-matrix engaphandle kweseli ezinqubweni ezijwayelekile zomzimba, njengokuthuthukiswa kombungu, ukukhiqizwa kabusha, ukuguqulwa kwezicubu, nezinqubo zezifo ezihlanganisa isifo samathambo kanye ne-metastasis.Njenge-endopeptidase encike ku-zinc eyimfihlo, i-MMP3 yenza imisebenzi yayo ikakhulukazi... -
Anti- human IGFBP-1 Antibody, Igundane Monoclonal
Imininingwane yomkhiqizo Ulwazi Olujwayelekile I-IGFBP1, eyaziwa nangokuthi i-IGFBP-1 kanye ne-insulin-like growth factor-binding protein 1, iyilungu lomndeni wamaprotheni abopha into efana ne-insulin.Amaprotheni abophezelayo e-IGF (IGFBPs) angamaprotheni angama-24 kuya ku-45 kDa.Wonke ama-IGFBP ayisithupha abelana nge-homology engu-50% futhi anezibopho ezibophezelayo ze-IGF-I ne-IGF-II ngendlela efanayo yobukhulu njengoba ama-ligand enawo we-IGF-IR.Amaprotheni abopha i-IGF andisa uhhafu wempilo yama-IGF futhi aboniswe ukuthi avimbela noma akhuthaze... -
Anti-human PLGF Antibody, Igundane Monoclonal
Imininingwane Yomkhiqizo Ulwazi Olujwayelekile I-Preeclampsia (PE) iyinkimbinkimbi enkulu yokukhulelwa ebonakala ngomfutho wegazi ophakeme kanye ne-proteinuria ngemva kwamasonto angu-20 okukhulelwa.I-Preeclampsia yenzeka ku-3-5 % wokukhulelwa futhi iphumela ekufeni komama noma kwengane noma kwezingane ezisanda kuzalwa kanye nokugula okukhulu.Ukubonakaliswa komtholampilo kungahluka kusuka kumafomu amancane kuya kwanzima;I-preeclampsia isengenye yezimbangela eziphambili zokugula nokufa kwengane kanye nomama.I-Preeclampsia ibonakala ibangelwa ukukhululwa ... -
Anti-human sFlt-1 Antibody, Igundane Monoclonal
Imininingwane Yomkhiqizo Ulwazi Olujwayelekile I-Preeclampsia iyinkimbinkimbi yokukhulelwa enezinhlelo eziningi, eyenzeka ku-3 - 5 % wokukhulelwa, futhi ingenye yezimbangela eziphambili zokugula nokufa komama nokushona kwelanga emhlabeni wonke.I-Preeclampsia ichazwa njengokuqalwa okusha komfutho wegazi ophakeme kanye ne-proteinuria ngemva kwamasonto angu-20 okukhulelwa.Isethulo somtholampilo se-preeclampsia kanye nenkambo yomtholampilo elandelayo yalesi sifo ingahluka kakhulu, okwenza ukubikezela, ukuxilongwa nokuhlola ... -
I-Anti-Human RBP4 Antibody, Igundane I-Monoclonal
Imininingwane yomkhiqizo Ulwazi Olujwayelekile I-retinol-binding protein 4 (RBP4) iwumthwalo othize we-retinol (ebuye yaziwe ngokuthi uvithamini A), futhi inesibopho sokuguqulwa kwe-retinol engaqinile nengancibiliki exazululeni elinamanzi ibe inkimbinkimbi ezinzile nencibilikayo ku-plasma ukusebenzisana.Njengelungu le-lipocalin superfamily, i-RBP4 equkethe isakhiwo se-β-barrel esinomgodi ochazwe kahle ikhishwa esibindini, bese ihambisa i-retinol isuka ezitolo zesibindi iye ku-periph... -
Anti-human VEGF Antibody, Igundane Monoclonal
Imininingwane Yomkhiqizo Ulwazi Olujwayelekile I-Vascular endothelial growth factor (VEGF), eyaziwa nangokuthi yi-vascular permeability factor (VPF) kanye ne-VEGF-A, ingumxhumanisi onamandla wakho kokubili i-angiogenesis kanye ne-vasculogenesis ku-fetus kanye nomuntu omdala.Iyilungu lomndeni we-platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF) futhi ngokuvamile iba khona njenge-homodimer exhunywe yi-disulfide.I-VEGF-A protein iyi-mitogen ye-glycosylated esebenza ngokukhethekile kumaseli e-endothelial futhi inemiphumela ehlukahlukene, kuhlanganisa ...
