I-Anti- human s100 β Antibody, Igundane I-Monoclonal
Imininingwane yomkhiqizo
Ulwazi oluvamile
I-S100B iyiphrotheni ebopha i-calcium, ekhishwa kuma-astrocyte.Iphrotheni encane ye-dimeric cytosolic (21 kDa) ehlanganisa i-ββ noma i-αβ chain.I-S100B ibandakanyeka ezinhlobonhlobo zemisebenzi yokulawula engaphakathi kweseli nengaphandle kwamaseli.
Kule minyaka eyishumi edlule, i-S100B iye yavela njenge-peripheral biomarker yomonakalo we-blood-brain barrier (BBB) kanye nokulimala kwe-CNS.Amazinga aphezulu e-S100B abonisa ngokunembile ukuba khona kwezimo ze-neuropathological kuhlanganise nokulimala kwekhanda okubuhlungu kanye nezifo ze-neurodegenerative.Amazinga ajwayelekile e-S100B ayifaki ngokuthembekile i-CNS pathology.I-Serum S100B nayo ibikwe njengophawu oluwusizo lokutholwa kusenesikhathi kwe-metastase ye-melanoma kanye nezinkinga zobuchopho ngenxa yokulimala ekhanda, ukuhlinzwa kwenhliziyo, kanye nokushaywa unhlangothi okuyingozi.
Izakhiwo
| Bhanqa Isincomo | I-CLIA (Ukutholwa-Thatha): 5H2-3 ~ 22G7-5 22G7-5 ~ 5H2-3 |
| Ubumsulwa | >95% njengoba kunqunywa i-SDS-PAGE. |
| Ukwakhiwa Kwesigcinalwazi | 20 mM PB, 150 mM NaCl, 0.1% Proclin 300,pH7.4 |
| Isitoreji | Igcine ngaphansi kwezimo eziyinyumba ku -20℃ ukuya ku -80 ℃ uma yamukelwa. Ncoma ukuthi i-aliquot iphrotheni ibe ngamanani amancane ukuze uthole isitoreji esiphezulu. |
Ukuqhathanisa Ngokuncintisana
Oda Ulwazi
| Igama Lomkhiqizo | Ikati.Cha | I-Clone ID |
| s100 b | AB0061-1 | 5H2-3 |
| I-AB0061-2 | 22G7-5 | |
| AB0061-3 | 21A6-1 |
Qaphela: I-Bioantibody ingakwazi ukwenza amanani ngendlela oyifisayo ngokwesidingo sakho.
Izingcaphuno
1. Ostendorp T , Leclerc E , Galicet A , et al.Imininingwane yesakhiwo nokusebenza kokuvula i-RAGE nge-multimeric S100B[J].I-EMBO Journal, 2007, 26(16):3868-3878.
2. R, D, Rothoerl, et al.Amazinga aphezulu e-serum S100B ezigulini ezihlukumezekile ezingenakulimala ekhanda.[J].I-Neurosurgery, 2001.
