• isibhengezo_somkhiqizo

I-Anti-Human RBP4 Antibody, Igundane I-Monoclonal

Incazelo emfushane:

Ukuhlanzwa I-Affinity-chromatography I-Isotype Akunqunyelwe
Izinhlobo Zokusingatha Igundane I-Species Reactivity Umuntu
Isicelo I-Chemiluminescent Immunoassay (CLIA)

Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Imininingwane yomkhiqizo

Ulwazi oluvamile
I-retinol-binding protein 4 (RBP4) ingumthwali othize we-retinol (owaziwa nangokuthi uvithamini A), futhi unesibopho sokuguqulwa kwe-retinol engazinzile nengancibiliki esixazululweni samanzi ibe inkimbinkimbi ezinzile nencibilikayo ku-plasma ngokusebenzisana kwayo okuqinile.Njengelungu le-lipocalin superfamily, i-RBP4 equkethe isakhiwo se-β-barrel esinomgodi ochazwe kahle ikhishwa esibindini, bese ihambisa i-retinol kusuka ezitolo zesibindi kuya ezicutshini ze-peripheral.Ku-plasma, inkimbinkimbi ye-RBP4-retinol isebenzisana ne-transthyretin (TTR), futhi lokhu kubopha kubalulekile ekuvimbeleni ukuphuma kwe-RBP4 nge-glomeruli yezinso.I-RBP4 evezwe emthonjeni we-ectopic iletha kahle i-retinol emehlweni, futhi ukuntula kwayo kuthinta kakhulu ukubona ebusuku.Muva nje, i-RBP4 njenge-adipokine, itholakala ukuthi ivezwe kuzicubu ze-adipose futhi ihlotshaniswa nokukhuluphala, ukumelana ne-insulin (IR) kanye nohlobo lwe-2 yesifo sikashukela (T2DM).

Izakhiwo

Bhanqa Isincomo I-CLIA (Ukutholwa-Thatha):
9D11-8 ~ 3D4-1
3C8-1 ~ 3D4-1
Ubumsulwa >95% njengoba kunqunywa i-SDS-PAGE.
Ukwakhiwa Kwesigcinalwazi I-PBS, pH7.4.
Isitoreji Igcine ngaphansi kwezimo eziyinyumba ku -20℃ ukuya ku -80 ℃ uma yamukelwa.
Ncoma ukuthi i-aliquot iphrotheni ibe ngamanani amancane ukuze uthole isitoreji esiphezulu.

Ukuqhathanisa Ngokuncintisana

IMINININGWANE (2)
IMINININGWANE (1)

Oda Ulwazi

Igama Lomkhiqizo Ikati.Cha I-Clone ID
I-RBP4 AB0032-1 9D11-8
AB0032-2 3C8-1
AB0032-3 3D4-1
AB0032-4 1C6-1

Qaphela: I-Bioantibody ingakwazi ukwenza amanani ngendlela oyifisayo ngokwesidingo sakho.

Izingcaphuno

1.Aiwei YB , Vijayalakshmi V , Bodles AM , et al.I-retinol ebopha iphrotheni yesi-4 kubantu: ubudlelwano nokumelana ne-insulin, ukuvuvukala, kanye nokusabela ku-pioglitazone.[J].I-J Clin Endocrinol Metab(7):2590-2597.

2.Haider DG , Karin S , Gerhard P , et al.I-Serum retinol-binding protein 4 yehliswa ngemva kokuncipha kwesisindo kubantu abakhuluphele ngokweqile.[J].Ijenali ye-Clinical Endocrinology & Metabolism (3): 1168-71.


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