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I-Anti-Human MPO Antibody, Igundane I-Monoclonal
Imininingwane yomkhiqizo Ulwazi Olujwayelekile MPO (i-myeloperoxidase) iyi-enzyme ye-peroxidase ekhiqizwe ama-leukocyte adlala indima ye-pathogenic esifweni senhliziyo nemithambo yegazi, ikakhulukazi ngokuqalisa ukungasebenzi kahle kwe-endothelial.I-Myeloperoxidase (MPO) iyi-enzyme ebalulekile, engenye yezingxenye zesistimu ye-antibacterial kuma-neutrophils nama-monocyte.I-MPO ibamba iqhaza ekuphenduleni ukuvuvukala ezindaweni eziningi emzimbeni, kuhlanganise nezindlala zebele.I-Myeloperoxidase (MPO), ingxenye ethile... -
I-anti-human GDF15 Antibody, Igundane I-Monoclonal
Imininingwane yomkhiqizo Ulwazi Olujwayelekile Lokukhula-umehluko factor 15 (GDF15), eyaziwa nangokuthi i-MIC-1, iyilungu eliyimfihlo le-transforming growth factor (TGF) -β superfamily, njengenoveli yokulawula i-antihypertrophic factor enhliziyweni.I-GDF-15 / GDF15 ayivezwa enhliziyweni yomuntu omdala evamile kodwa yenziwa ngokuphendula izimo ezikhuthaza i-hypertrophy kanye ne-dilated cardiomyopathy futhi ivezwa kakhulu esibindini.I-GDF-15 / GDF15 inendima ekulawuleni indlela yokuvuvukala kanye ne-apoptotic... -
I-anti- human Lp-PLA2 Antibody, Igundane Monoclonal
Imininingwane yomkhiqizo Ulwazi Olujwayelekile I-phospholipase A2 (Lp-PLA2) ehlotshaniswa ne-Lipoprotein (Lp-PLA2) ikhiqizwa amaseli avuvukalayo futhi ijikeleze ngokuyinhloko iboshwe ku-low-density lipoprotein (LDL) futhi ngokwezinga elincane ihlotshaniswa ne-high-density lipoprotein (HDL) ku-plasma yomuntu.I-LDL oxidation yaziwa njengesenzakalo sokuqala esiyinhloko ku-pathogenesis ye-atherosclerosis.Amazinga aphezulu e-Lp-PLA2 atholakale kuma-atherosclerotic plaque kanye nezilonda zokuphuka.Izincomo Zokubhangqa Kwezakhiwo I-CLIA (Capture-De... -
Anti-human GH Antibody, Igundane Monoclonal
Imininingwane yomkhiqizo Ihomoni Yokukhula Kolwazi Olujwayelekile (GH) noma i-somatotropin, eyaziwa nangokuthi i-hormone yokukhula komuntu (hGH noma i-HGH), iyihomoni ye-peptide ekhuthaza ukukhula, ukukhiqizwa kwamangqamuzana, nokuvuselelwa kwamaseli kubantu nakwezinye izilwane.Ngakho ibalulekile ekuthuthukisweni komuntu.I-GH iphinde ikhuthaze ukukhiqizwa kwe-IGF-1 futhi ikhulise ukugxila kweglucose kanye nama-fatty acids mahhala.Iwuhlobo lwe-mitogen oluqondene kuphela nama-receptors ezinhlotsheni ezithile zamaseli.I-GH iyi-191-amino acid, ... -
Anti-human PRL Antibody, Igundane Monoclonal
Imininingwane yomkhiqizo Ulwazi Olujwayelekile I-Prolactin (PRL), eyaziwa nangokuthi i-lactotropin, iyihomoni eyenziwe yindlala ye-pituitary, indlala encane engaphansi kobuchopho.I-Prolactin ibangela ukuthi amabele akhule futhi enze ubisi ngesikhathi sokukhulelwa nangemva kokuzalwa.Amazinga e-prolactin ngokuvamile aphezulu kwabesifazane abakhulelwe nomama abasha.Amazinga avamise ukuba aphansi kwabesifazane abangakhulelwe nakwabesilisa.Ukuhlolwa kwamazinga eprolactin kuvame ukusetshenziselwa: ★ Ukuthola i-prolactinoma (uhlobo lwesimila se-pituitary gland) ★ Usizo... -
I-Anti-Human SHBG Antibody, Igundane Monoclonal
Imininingwane yomkhiqizo Ulwazi Olujwayelekile Ihomoni ebopha i-globulin yocansi (SHBG) iyi-glycoprotein engaba ngu-80-100 kDa;inobudlelwane obuphezulu be-17 beta-hydroxysteroid hormones njenge-testosterone ne-estradiol.Ukugxila kwe-SHBG ku-plasma kulawulwa, phakathi kwezinye izinto, ibhalansi ye-androgen/estrogen, amahomoni egilo, i-insulin kanye nezici zokudla.Kuyiprotheni yokuthutha ebaluleke kakhulu yama-estrogens nama-androgens egazini le-peripheral.Ukugxila kwe-SHBG kuyisici esikhulu esilawula ukungazi kwabo ... -
Anti-human calprotectin Antibody, Igundane Monoclonal
Imininingwane yomkhiqizo Ulwazi Olujwayelekile I-Calprotectin iphrotheni ekhishwa uhlobo lwengqamuzana elimhlophe legazi elibizwa ngokuthi i-neutrophil.Uma kukhona ukuvuvukala emgudwini wesisu (GI), ama-neutrophil athuthela endaweni futhi akhulule i-calprotectin, okuholela ekukhuphukeni kwezinga esitulweni.Ukulinganisa izinga le-calprotectin esitulweni kuyindlela ewusizo yokuthola ukuvuvukala emathunjini.Ukuvuvukala kwamathumbu kuhlotshaniswa nesifo samathumbu esivuvukalayo (IBD) kanye nokunye okungenwa yi-bacterial GI... -
I-IL6 ye-anti-human, i-Mouse Monoclonal
Imininingwane yomkhiqizo Ulwazi Olujwayelekile I-Interleukin-6 (IL-6) iyi-cytokine ye-α-helical enemisebenzi eminingi elawula ukukhula kwamangqamuzana nokuhlukaniswa kwezicubu ezihlukahlukene, eyaziwa ikakhulukazi ngendima yayo ekuphenduleni kokuzivikela komzimba kanye nokusabela kwesigaba esibucayi.Iphrotheni ye-IL-6 ikhiqizwa izinhlobo ezahlukene zamaseli okuhlanganisa amaseli e-T nama-macrophage njenge-molecule ye-phosphorylated ne-glycosylated eguquguqukayo.Isebenzisa isenzo ngesamukeli sayo se-heterodimeric esakhiwe i-IL-6R engenayo i-tyrosine/kinas... -
Anti-human MMP-3 Antibody, Igundane Monoclonal
Imininingwane yomkhiqizo Ulwazi Olujwayelekile I-Matrix metallopeptidase 3 (efushanisiwe njenge-MMP3) yaziwa nangokuthi i-stromelysin 1 ne-progelatinase.I-MMP3 iyilungu lomndeni we-matrix metalloproteinase (MMP) amalungu awo abambe iqhaza ekuqhekekeni kwe-matrix engaphandle kweseli ezinqubweni ezijwayelekile zomzimba, njengokuthuthukiswa kombungu, ukukhiqizwa kabusha, ukuguqulwa kwezicubu, nezinqubo zezifo ezihlanganisa isifo samathambo kanye ne-metastasis.Njenge-endopeptidase encike ku-zinc eyimfihlo, i-MMP3 yenza imisebenzi yayo ikakhulukazi... -
Anti- human IGFBP-1 Antibody, Igundane Monoclonal
Imininingwane yomkhiqizo Ulwazi Olujwayelekile I-IGFBP1, eyaziwa nangokuthi i-IGFBP-1 kanye ne-insulin-like growth factor-binding protein 1, iyilungu lomndeni wamaprotheni abopha into efana ne-insulin.Amaprotheni abophezelayo e-IGF (IGFBPs) angamaprotheni angama-24 kuya ku-45 kDa.Wonke ama-IGFBP ayisithupha abelana nge-homology engu-50% futhi anezibopho ezibophezelayo ze-IGF-I ne-IGF-II ngendlela efanayo yobukhulu njengoba ama-ligand enawo we-IGF-IR.Amaprotheni abopha i-IGF andisa uhhafu wempilo yama-IGF futhi aboniswe ukuthi avimbela noma akhuthaze... -
Anti-human PLGF Antibody, Igundane Monoclonal
Imininingwane Yomkhiqizo Ulwazi Olujwayelekile I-Preeclampsia (PE) iyinkimbinkimbi enkulu yokukhulelwa ebonakala ngomfutho wegazi ophakeme kanye ne-proteinuria ngemva kwamasonto angu-20 okukhulelwa.I-Preeclampsia yenzeka ku-3-5 % wokukhulelwa futhi iphumela ekufeni komama noma kwengane noma kwezingane ezisanda kuzalwa kanye nokugula okukhulu.Ukubonakaliswa komtholampilo kungahluka kusuka kumafomu amancane kuya kwanzima;I-preeclampsia isengenye yezimbangela eziphambili zokugula nokufa kwengane kanye nomama.I-Preeclampsia ibonakala ibangelwa ukukhululwa ... -
Anti-human sFlt-1 Antibody, Igundane Monoclonal
Imininingwane Yomkhiqizo Ulwazi Olujwayelekile I-Preeclampsia iyinkimbinkimbi yokukhulelwa enezinhlelo eziningi, eyenzeka ku-3 - 5 % wokukhulelwa, futhi ingenye yezimbangela eziphambili zokugula nokufa komama nokushona kwelanga emhlabeni wonke.I-Preeclampsia ichazwa njengokuqalwa okusha komfutho wegazi ophakeme kanye ne-proteinuria ngemva kwamasonto angu-20 okukhulelwa.Isethulo somtholampilo se-preeclampsia kanye nenkambo yomtholampilo elandelayo yalesi sifo ingahluka kakhulu, okwenza ukubikezela, ukuxilongwa nokuhlola ...
