Anti-human AFP Antibody, Igundane Monoclonal
Imininingwane yomkhiqizo
Ulwazi oluvamile
I-Alpha-fetoprotein (AFP) ihlukaniswa njengelungu le-albuminoid gene superfamily ehlanganisa i-albumin, AFP, vitamin D (Gc) protein, ne-alpha-albumin.I-AFP iyi-glycoprotein enama-amino acid angama-591 kanye nengxenye ye-carbohydrate.I-AFP ingelinye lamaprotheni athile aqondene nombungu futhi iyiphrotheni ye-serum ebusayo ekuqaleni kwempilo yombungu womuntu njengenyanga eyodwa, lapho i-albumin ne-transferrin zikhona ngamanani amancane uma kuqhathaniswa.Iqala ukuhlanganiswa kumuntu ngesaka le-yolk nesibindi (izinyanga ezi-1-2) futhi kamuva ibe sesibindini.Inani elincane le-AFP likhiqizwa ipheshana le-GI lomqondo womuntu.Kufakazelwe ukuthi i-AFP ingase iphinde ivele ku-serum ngamanani aphakeme empilweni yabantu abadala ngokuhambisana nezinqubo ezivamile zokubuyisela kanye nokukhula okubi.I-Alpha-fetoprotein (AFP) iwuphawu oluthile lwe-hepatocellular carcinoma (HCC), i-teratoblastomas, kanye ne-neural tube defect (NTD).
Izakhiwo
| Bhanqa Isincomo | I-CLIA (Ukutholwa-Thatha): 3C8-6 ~ 11D1-2 8A3-7 ~ 11D1-2 |
| Ubumsulwa | >95%, kunqunywa i-SDS-PAGE |
| Ukwakhiwa Kwesigcinalwazi | I-PBS, pH7.4. |
| Isitoreji | Yigcine ngaphansi kwezimo eziyinyumba ku -20℃kuye -80℃ekutholeni. Ncoma ukuthi i-aliquot iphrotheni ibe ngamanani amancane ukuze uthole isitoreji esiphezulu. |
Ukuhlaziya Ukuqhathanisa
Oda Ulwazi
| Igama Lomkhiqizo | Ikati.Cha | I-Clone ID |
| I-AFP | AB0069-1 | 11D1-2 |
| I-AB0069-2 | 3C8-6 | |
| AB0069-3 | 8A3-7 |
Qaphela: I-Bioantibody ingakwazi ukwenza amanani ngendlela oyifisayo ngokwesidingo sakho.
Izingcaphuno
1.Mizejewski GJ.(2001) Isakhiwo Nomsebenzi we-Alpha-fetoprotein: Ukufaneleka Kwama-Isoform, Ama-Epitopes, Nokuhlukahluka Okuhambisanayo.Exp Biol Med.226(5): 377-408.
2.Tomasi TB, et al.(1977) Isakhiwo kanye nomsebenzi we-Alpha-Fetoprotein.Ukubuyekezwa Kwemithi Yonyaka.28:453-65.
3.Leguy MC, et al.(2011) Ukuhlolwa kwe-AFP ku-amniotic fluid: ukuqhathaniswa kwamasu amathathu okuzenzakalelayo.U-Ann Biol Clin.69(4): 441-6.
