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Ama-Raw material
I-antibody
I-Anti-Flu A Antibody, Igundane I-Monoclonal
Imininingwane Yomkhiqizo Ulwazi Olujwayelekile Umkhuhlane, noma umkhuhlane, isifo esithathelwanayo esibangelwa amagciwane omkhuhlane.Izimpawu zomkhuhlane zihlanganisa ubuhlungu bemisipha nobuhlungu, ikhanda elibuhlungu, nomkhuhlane.Igciwane lomkhuhlane wohlobo A lihlala lishintsha futhi ngokuvamile libangela ubhadane lomkhuhlane omkhulu.Umkhuhlane A ungahlukaniswa ube yizinhlobo ezincane ezihlukene ngokusekelwe ekuhlanganisweni kwamaprotheni amabili endaweni yegciwane: i-hemagglutinin (H) ne-neuraminidase (N).Izincomo zokubhanqa kwezakhiwo...
imininingwane
Anti-human Her2 Antibody, Igundane Monoclonal
Imininingwane Yomkhiqizo Ulwazi Olujwayelekile I-Human epidermal growth factor receptor 2 (HER2), eyaziwa nangokuthi i-ErbB2, NEU, ne-CD340, iwuhlobo I-membrane glycoprotein futhi iyingxenye yomndeni wama-epidermal growth factor (EGF).Iphrotheni ye-HER2 ayikwazi ukubopha izici zokukhula ngenxa yokushoda kwesizinda esibophezelayo se-ligand esayo futhi esivimbele ngokuzenzakalelayo.Kodwa-ke, i-HER2 yakha i-heterodimer namanye amalungu omndeni we-EGF receptor eboshwe nge-ligand, ngakho-ke iqinisa ukubopha kwe-ligand futhi ithuthukise i-kinas...
imininingwane
I-Anti- human s100 β Antibody, Igundane Monoclonal
Imininingwane yomkhiqizo Ulwazi Olujwayelekile I-S100B iphrotheni ebopha i-calcium, ekhishwa kuma-astrocyte.Iphrotheni encane ye-dimeric cytosolic (21 kDa) ehlanganisa i-ββ noma i-αβ chain.I-S100B ibandakanyeka ezinhlobonhlobo zemisebenzi yokulawula engaphakathi kweseli nengaphandle kwamaseli.Kule minyaka eyishumi edlule, i-S100B iye yavela njenge-peripheral biomarker yomonakalo we-blood-brain barrier (BBB) kanye nokulimala kwe-CNS.Amazinga aphakanyisiwe e-S100B abonisa ngokunembile ukuba khona kwezimo ze-neuropathological ku...
imininingwane
Anti-human GH Antibody, Igundane Monoclonal
Imininingwane yomkhiqizo Ihomoni Yokukhula Kolwazi Olujwayelekile (GH) noma i-somatotropin, eyaziwa nangokuthi i-hormone yokukhula komuntu (hGH noma i-HGH), iyihomoni ye-peptide ekhuthaza ukukhula, ukukhiqizwa kwamangqamuzana, nokuvuselelwa kwamaseli kubantu nakwezinye izilwane.Ngakho kubalulekile ekuthuthukisweni komuntu.I-GH iphinde ikhuthaze ukukhiqizwa kwe-IGF-1 futhi ikhulise ukugxila kwe-glucose kanye nama-fatty acids mahhala.Iwuhlobo lwe-mitogen oluqondene kuphela nama-receptors ezinhlotsheni ezithile zamaseli.I-GH iyi-191-amino ...
imininingwane
Anti-human PRL Antibody, Igundane Monoclonal
Imininingwane yomkhiqizo Ulwazi Olujwayelekile I-Prolactin (PRL), eyaziwa nangokuthi i-lactotropin, iyihomoni eyenziwe yindlala ye-pituitary, indlala encane ephansi kobuchopho.I-Prolactin idala ukuthi amabele akhule futhi enze ubisi ngesikhathi sokukhulelwa nangemva kokuzalwa.Amazinga e-prolactin ngokuvamile aphezulu kwabesifazane abakhulelwe nomama abasanda kuzalwa.Amazinga avamise ukuthi aphansi kwabesifazane abangakhulelwe nakwabesilisa.Ukuhlolwa kwamazinga e-prolactin kuvame ukusetshenziselwa: ★ Ukuthola i-prolactinoma (uhlobo lwesimila se-pituitary gland) ★...
imininingwane
Anti-human calprotectin Antibody, Igundane Monoclonal
Imininingwane yomkhiqizo Ulwazi Olujwayelekile I-Calprotectin iphrotheni ekhishwa uhlobo lwengqamuzana elimhlophe legazi elibizwa ngokuthi i-neutrophil.Uma kukhona ukuvuvukala emgudwini wesisu (GI), ama-neutrophil athuthela endaweni futhi akhulule i-calprotectin, okuholela ekukhuphukeni kwezinga esitulweni.Ukulinganisa izinga le-calprotectin esitulweni kuyindlela ewusizo yokuthola ukuvuvukala emathunjini.Ukuvuvukala kwamathumbu kuhlotshaniswa nesifo sofuba (IBD) kanye ne-GI ethile yebhaktheriya ...
imininingwane
I-Anti-Human RBP4 Antibody, Igundane I-Monoclonal
Imininingwane Yomkhiqizo Ulwazi Olujwayelekile I-retinol-binding protein 4 (RBP4) iwumthwalo othize we-retinol (ebuye yaziwe ngokuthi uvithamini A), futhi inesibopho sokuguqulwa kwe-retinol engaqinile nengancibiliki exukwini elinamanzi ibe inkimbinkimbi ezinzile nencibilikayo ku-plasma ukusebenzisana.Njengelungu le-lipocalin superfamily, i-RBP4 equkethe isakhiwo se-β-barrel esinomgodi ochazwe kahle ikhishwa esibindini, bese ihambisa i-retinol kusuka ezitolo zesibindi kuya ...
imininingwane
I-Anti-Human GDF15 Antibody, Igundane I-Monoclonal
Imininingwane yomkhiqizo Ulwazi Olujwayelekile Lokukhula-umehluko factor 15 (GDF15), eyaziwa nangokuthi i-MIC-1, iyilungu eliyimfihlo le-transforming growth factor (TGF) -β superfamily, njengenoveli yokulawula i-antihypertrophic factor enhliziyweni.I-GDF-15 / GDF15 ayivezwa enhliziyweni yomuntu omdala evamile kodwa yenziwa ngokuphendula izimo ezikhuthaza i-hypertrophy kanye ne-dilated cardiomyopathy futhi ivezwa kakhulu esibindini.I-GDF-15 / GDF15 inendima ekulawuleni ukuvuvukala kanye ne-apoptotic pa...
imininingwane
Anti-human sFlt-1 Antibody, Igundane Monoclonal
Imininingwane Yomkhiqizo Ulwazi Olujwayelekile I-Preeclampsia iyinkimbinkimbi yokukhulelwa enezinhlelo eziningi, eyenzeka ku-3 - 5 % wokukhulelwa, futhi ingenye yezimbangela eziphambili zokugula nokufa komama nokushona kwelanga emhlabeni wonke.I-Preeclampsia ichazwa njengokuqalwa okusha komfutho wegazi ophakeme kanye ne-proteinuria ngemva kwamasonto angu-20 okukhulelwa.Isethulo somtholampilo se-preeclampsia kanye nenkambo yomtholampilo elandelayo yalesi sifo ingahluka kakhulu, okwenza ukubikezela, ukuxilongwa nokuhlola ...
imininingwane
Anti-human PLGF Antibody, Igundane Monoclonal
Imininingwane Yomkhiqizo Ulwazi Olujwayelekile I-Preeclampsia (PE) iyinkimbinkimbi yokukhulelwa ebonakala ngomfutho wegazi ophakeme kanye ne-proteinuria ngemva kwamasonto angu-20 okukhulelwa.I-Preeclampsia yenzeka ku-3-5 % wokukhulelwa futhi iphumela ekufeni komama noma kwengane noma kwezingane ezisanda kuzalwa kanye nokugula okukhulu.Ukubonakaliswa komtholampilo kungahluka kusuka kumafomu amancane kuya kwanzima;I-preeclampsia isengenye yezimbangela eziphambili zokugula nokufa kwengane kanye nomama.I-Preeclampsia ibonakala ibangelwa ukukhishwa ...
imininingwane
Anti- human IGFBP-1 Antibody, Igundane Monoclonal
Imininingwane yomkhiqizo Ulwazi Olujwayelekile I-IGFBP1, eyaziwa nangokuthi i-IGFBP-1 kanye ne-insulin-like growth factor-binding protein 1, iyilungu lomndeni wamaprotheni abopha into efana ne-insulin.Amaprotheni abophezelayo e-IGF (IGFBPs) angamaprotheni angama-24 kuya ku-45 kDa.Wonke ama-IGFBP ayisithupha abelana nge-homology engu-50% futhi anezibopho ezibophezelayo ze-IGF-I ne-IGF-II ngendlela efanayo yobukhulu njengoba ama-ligand enawo we-IGF-IR.Amaprotheni abopha i-IGF andisa uhhafu wempilo yama-IGF futhi aboniswe ukuthi avimbela noma ...
imininingwane
I-anti-human MMP-3 Antibody, Igundane I-Monoclonal
Imininingwane yomkhiqizo Ulwazi Olujwayelekile I-Matrix metallopeptidase 3 (efushanisiwe njenge-MMP3) yaziwa nangokuthi i-stromelysin 1 ne-progelatinase.I-MMP3 iyilungu lomndeni we-matrix metalloproteinase (MMP) amalungu awo abambe iqhaza ekuqhekekeni kwe-matrix engaphandle kweseli ezinqubweni ezijwayelekile zomzimba, njengokuthuthukiswa kombungu, ukukhiqizwa kabusha, ukuguqulwa kwezicubu, nezinqubo zezifo ezihlanganisa isifo samathambo kanye ne-metastasis.Njenge-endopeptidase encike ku-zinc eyimfihlo, i-MMP3 yenza imisebenzi yayo ...
imininingwane
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