Ulwazi oluvamile
I-MPO (i-myeloperoxidase) iyi-enzyme ye-peroxidase ekhiqizwa ama-leukocyte acushiwe adlala indima ye-pathogenic esifweni senhliziyo, ikakhulukazi ngokuqalisa ukungasebenzi kahle kwe-endothelial.I-Myeloperoxidase (MPO) iyi-enzyme ebalulekile, engenye yezingxenye zesistimu ye-antibacterial kuma-neutrophils nama-monocyte.I-MPO ibamba iqhaza ekuphenduleni ukuvuvukala ezindaweni eziningi emzimbeni, kuhlanganise nezindlala zebele.I-Myeloperoxidase (MPO), i-enzyme ethize ye-polymorphonuclear leukocyte, isetshenziswe ngaphambilini ukuze kulinganiswe inani lama-neutrophils ezicutshini.Umsebenzi we-MPO utholwe uhlobene ngokuqondile nenani lamaseli e-neutrophil.Uhlelo lwe-MPO ludlala indima ebalulekile ekulawuleni izifo kanye nokususwa kwamaseli ayingozi.Noma kunjalo, ukushintshashintsha ohlelweni lwe-MPO kungaholela ekulimaleni kwe-DNA kanye ne-carcinogenesis.Ama-polymorphisms kufuzo lwe-MPO ahlotshaniswe nokubonakaliswa okwandisiwe kwe-MPO kanye nengozi enkulu yokukhula komdlavuza.I-Myeloperoxidase (MPO) ingelinye lama-antigen ahlosiwe amakhulu e-antineutrophil cytoplasmic autoantibodies (ANCA) atholakala ezigulini ezine-vasculitis yemithambo emincane kanye ne-Pauci-immune necrotizing glomerulonephritis.I-Myeloperoxidase-anti-neutrophil cytoplasmic antibody (MPO-ANCA) iyi-autoantibody evame ukutholakala ezigulini ezine-vasculitides.
Bhanqa Isincomo | I-CLIA (Ukutholwa-Thatha): 4D12-3 ~ 2C1-8 4C16-1 ~ 2C1-8 |
Ubumsulwa | >95%, kunqunywa i-SDS-PAGE |
Ukwakhiwa Kwesigcinalwazi | I-PBS, pH7.4. |
Isitoreji | Igcine ngaphansi kwezimo eziyinyumba ku -20℃ ukuya ku -80 ℃ uma yamukelwa. Ncoma ukuthi i-aliquot iphrotheni ibe ngamanani amancane ukuze uthole isitoreji esiphezulu. |
Igama Lomkhiqizo | Ikati.Cha | I-Clone ID |
I-MPO | AB0007-1 | 2C1-8 |
AB0007-2 | 4D12-3 | |
AB0007-3 | 4C16-1 |
Qaphela: I-Bioantibody ingakwazi ukwenza amanani ngendlela oyifisayo ngokwesidingo sakho.
1.Klebanoff, S. J.I-Myeloperoxidase: umngane nesitha[J].J Leukoc Biol, 2005, 77 (5): 598-625.
2.Baldus, S. Myeloperoxidase Amazinga Serum Abikezela Ingozi Ezigulini Ezine-Acute Coronary Syndrome[J].Ukujikeleza, 2003, 108(12):1440.