• isibhengezo_somkhiqizo

I-Anti-Human SHBG Antibody, Igundane Monoclonal

Incazelo emfushane:

Ukuhlanzwa I-Affinity-chromatography I-Isotype Akunqunyelwe
Izinhlobo Zokusingatha Igundane I-Species Reactivity Umuntu
Isicelo I-Chemiluminescent Immunoassay (CLIA)/Immunochromatography(IC)

Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Imininingwane yomkhiqizo

Ulwazi oluvamile
I-hormone yocansi ebopha i-globulin (SHBG) iyi-glycoprotein engaba ngu-80-100 kDa;inobudlelwane obuphezulu be-17 beta-hydroxysteroid hormones njenge-testosterone ne-estradiol.I-SHBG
Ukugxila ku-plasma kulawulwa, phakathi kwezinye izinto, ibhalansi ye-androgen/estrogen, amahomoni egilo, i-insulin kanye nezici zokudla.Kuyiprotheni yokuthutha ebaluleke kakhulu yama-estrogens nama-androgens egazini le-peripheral.Ukugxila kwe-SHBG kuyisici esikhulu esilawula ukusatshalaliswa kwazo phakathi kwezifunda eziboshwe ngamaprotheni nezikhululekile.Ukugxila kwe-Plasma SHBG kukhona
ezithintekayo ngenani lezifo ezihlukahlukene, amanani aphezulu atholakala ku-hyperthyroidism, hypogonadism, ukungezwani kwe-androgen kanye ne-hepatic cirrhosis emadodeni.Ukugxila okuphansi kutholakala ku-myxoedema, hyperprolactinemia kanye nama-syndromes omsebenzi we-androgen oweqile.Ukukalwa kwe-SHBG kuyasiza ekuhloleni ukuphazamiseka okuncane kwe-androgen metabolism futhi kuvumela ukuhlonzwa kwalabo besifazane abane-hirsutism okungenzeka basabele ekwelashweni kwe-estrogen.

Izakhiwo

Bhanqa Isincomo I-CLIA (Ukutholwa-Thatha):
3E10-1 ~ 3A10-5
3A10-5 ~ 3D8-2
Ubumsulwa >95%, kunqunywa i-SDS-PAGE
Ukwakhiwa Kwesigcinalwazi I-PBS, pH7.4.
Isitoreji Igcine ngaphansi kwezimo eziyinyumba ku -20℃ ukuya ku -80 ℃ uma yamukelwa.
Ncoma ukuthi i-aliquot iphrotheni ibe ngamanani amancane ukuze uthole isitoreji esiphezulu.

Ukuqhathanisa Ngokuncintisana

imininingwane (2)
imininingwane (1)

Oda Ulwazi

Igama Lomkhiqizo Ikati.Cha I-Clone ID
SHBG AB0030-1 3A10-5
AB0030-2 3E10-1
AB0030-3 3D8-2

Qaphela: I-Bioantibody ingakwazi ukwenza amanani ngendlela oyifisayo ngokwesidingo sakho.

Izingcaphuno

1. I-Selby C. I-hormone yocansi ebopha i-globulin: imvelaphi, umsebenzi kanye nokubaluleka komtholampilo.U-Ann Clin Biochem 1990; 27:532-541.

2. Pugeat M, Crave JC, Tourniare J, et al.Isisetshenziswa somtholampilo se-sex hormone ebopha isilinganiso se-globulin.I-Horm Res 1996;45(3-5):148-155.


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