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Anti-human IL6 Antibody, Igundane Monoclonal
Imininingwane yomkhiqizo Ulwazi Olujwayelekile I-Interleukin-6 (IL-6) iyi-cytokine ye-α-helical esebenza ngezindlela eziningi elawula ukukhula kwamangqamuzana nokuhlukaniswa kwezicubu ezihlukahlukene, eyaziwa ikakhulukazi ngendima yayo ekuphenduleni kokuzivikela komzimba kanye nokusabela kwesigaba esibucayi.Iphrotheni ye-IL-6 ikhiqizwa izinhlobo ezahlukene zamaseli okuhlanganisa amaseli e-T nama-macrophages njenge-molecule ye-phosphorylated ne-glycosylated eguquguqukayo.Isebenzisa isenzo ngesamukeli sayo se-heterodimeric esakhiwe i-IL-6R engenayo i-tyrosine/... -
I-Anti-Human SHBG Antibody, Igundane Monoclonal
Imininingwane yomkhiqizo Ulwazi Olujwayelekile Ihomoni ebopha i-globulin yocansi (SHBG) iyi-glycoprotein engaba ngu-80-100 kDa;inobudlelwane obuphezulu be-17 beta-hydroxysteroid hormones njenge-testosterone ne-estradiol.Ukugxila kwe-SHBG ku-plasma kulawulwa, phakathi kwezinye izinto, ibhalansi ye-androgen/estrogen, amahomoni egilo, i-insulin kanye nezici zokudla.Kuyiprotheni yokuthutha ebaluleke kakhulu yama-estrogens nama-androgens egazini le-peripheral.Ukugxila kwe-SHBG kuyisici esikhulu esilawula ... -
I-Anti-Human MPO Antibody, Igundane I-Monoclonal
Imininingwane yomkhiqizo Ulwazi Olujwayelekile MPO (i-myeloperoxidase) iyi-enzyme ye-peroxidase ekhiqizwe ama-leukocyte adlala indima ye-pathogenic esifweni senhliziyo nemithambo yegazi, ikakhulukazi ngokuqalisa ukungasebenzi kahle kwe-endothelial.I-Myeloperoxidase (MPO) iyi-enzyme ebalulekile, engenye yezingxenye zesistimu ye-antibacterial kuma-neutrophils nama-monocyte.I-MPO ibamba iqhaza ekuphenduleni kokuvuvukala ezindaweni eziningi emzimbeni, okuhlanganisa nezindlala zebele.I-Myeloperoxidase (MPO), i-speci... -
I-Anti- human Lp-PLA2 Antibody, Igundane Monoclonal
Imininingwane Yomkhiqizo Ulwazi Olujwayelekile I-phospholipase A2 (Lp-PLA2) ehlotshaniswa ne-Lipoprotein (Lp-PLA2) ikhiqizwa amaseli avuvukalayo futhi ijikeleze ngokuyinhloko iboshwe ku-low-density lipoprotein (LDL) futhi ngokwezinga elincane ihlotshaniswa ne-high-density lipoprotein (HDL) ku-plasma yomuntu.I-LDL oxidation yaziwa njengesenzakalo sokuqala esiyinhloko ku-pathogenesis ye-atherosclerosis.Amazinga aphezulu e-Lp-PLA2 atholwe kuma-atherosclerotic plaque kanye nezilonda zokuphuka.Izincomo Zokubhangqa Kwezakhiwo I-CLIA ... -
Anti-human VEGFA Antibody, Igundane Monoclonal
Imininingwane yomkhiqizo Ulwazi Olujwayelekile I-Vascular endothelial growth factor (VEGF), eyaziwa nangokuthi yi-vascular permeability factor (VPF) kanye ne-VEGF-A, ingumxhumanisi onamandla wakho kokubili i-angiogenesis kanye ne-vasculogenesis ku-fetus kanye nomuntu omdala.Iyilungu lomndeni we-platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF) futhi ngokuvamile iba khona njenge-homodimer exhunywe yi-disulfide.I-VEGF-A protein iyi-mitogen ene-glycosylated esebenza ngokukhethekile kumaseli e-endothelial futhi inemiphumela ehlukahlukene... -
I-anti- human TIMP1 Antibody, Igundane i-Monoclonal
Imininingwane yomkhiqizo Ulwazi Olujwayelekile I-TIMP metallopeptidase inhibitor 1, eyaziwa nangokuthi i-TIMP-1/TIMP1, i-Collagenase inhibitor 16C8 fibroblast Umsebenzi we-Erythroid-potentiating, i-TPA-S1TPA-induced proteinI-Tissue inhibitor of metalloproteinases 1, iyi-metalloproteinase yemvelo ye-MloMP iqembu lama-peptidase elihilelekile ekucekeleni phansi kwe-matrix engaphandle kwamaseli.I-TIMP-1/TIMP1 itholakala kuzicubu ze-fetus nezindala.Amazinga aphezulu kakhulu atholakala emathanjeni, emaphashini, e-ovary nasesibelethweni.Inkimbinkimbi... -
Anti- human PIVKA -II Antibody, Igundane Monoclonal
Imininingwane Yomkhiqizo Ulwazi Olujwayelekile Iphrotheni Ebangelwa Ukungabi Nakho Kwe-Vitamin K noma I-Antagonist-II (PIVKA-II), eyaziwa nangokuthi i-Des-γ-carboxy-prothrombin (DCP), iwuhlobo olungavamile lwe-prothrombin.Imvamisa, izinsalela ze-prothrombin eziyi-10 ze-glutamic acid (Glu) kusizinda se-γ-carboxyglutamic acid (Gla) ezikhundleni 6, 7, 14, 16, 19, 20,25, 26, 29 kanye ne-32 ziyi-γ-carboxylated ku-Glasi ngevithamini. -K encike ku-γ- glutamyl carboxylase esibindini bese ikhishelwa ku-plasma.Ezigulini ezinemoto ye-hepatocellular... -
Anti-human PG II Antibody, Igundane Monoclonal
Imininingwane yomkhiqizo Ulwazi Olujwayelekile I-Pepsinogen iwuhlobo lwe-pepsin futhi ikhiqizwa amaseli amakhulu esiswini.Ingxenye enkulu ye-pepsinogen ikhishwa ku-lumen yesisu kodwa inani elincane lingatholakala egazini.Izinguquko ekugxilweni kwe-serum pepsinogen zitholwe ngezifo ze-Helicobacter pylori (H. Pylori), isifo se-peptic ulcer, i-gastritis, nomdlavuza wesisu.Ukuhlaziya okunembe kakhudlwana kungase kuzuzwe ngokulinganisa isilinganiso se-pepsinogen I/II.Izakhiwo ... -
Anti-human PGI Antibody, Igundane Monoclonal
Imininingwane yomkhiqizo Ulwazi Olujwayelekile I-Pepsinogen I, izandulela ze-pepsin, ikhiqizwa ulwelwesi lwesisu bese ikhishelwa kulume lwesisu kanye nokujikeleza kwe-peripheral.I-Pepsinogen iqukethe iketango elilodwa le-polypeptide lama-amino acid angama-375 anesisindo semolekyuli esiyisilinganiso esingu-42 kD.I-PG I (isoenzyme 1-5) ikhiqizwa ikakhulukazi amaseli ayinhloko ku-fundac mucosa, kuyilapho i-PG II (isoenzyme 6-7) ikhishwa yizindlala ze-pyloric kanye ne-proximal duodenal mucosa.Isandulela sibonisa izinombolo ze-s... -
I-Anti- human CHI3L1 Antibody, i-Monoclonal yomuntu
Imininingwane yomkhiqizo Ulwazi Olujwayelekile I-Chitinase-3-like protein 1 (CHI3L1) iyi-glycoprotein ebopha i-heparin eyimfihlo ukusho kwayo kuhlotshaniswa nokufuduka kwamaseli emisipha ebushelelezi.I-CHI3L1 iboniswa emazingeni aphezulu kumasiko e-postconfluent nodular VSMC kanye namazinga aphansi kumasiko akhulayo angaphansi.I-CHI3L1 iyi-lectin enethishu ekhawulelwe, ebophezela i-chitin futhi iyilungu lomndeni we-glycosyl hydrolase 18. Ngokungafani nezinye izimpawu eziningi ze-monocyto / macrophage, isisho sayo ... -
Anti-human AFP Antibody, Igundane Monoclonal
Imininingwane yomkhiqizo Ulwazi Olujwayelekile I-Alpha-fetoprotein (AFP) ihlukaniswa njengelungu lomndeni omkhulu we-albuminoid ohlanganisa i-albumin, AFP, vitamin D (Gc) protein, kanye ne-alpha-albumin.I-AFP iyi-glycoprotein enama-amino acid angama-591 kanye nengxenye ye-carbohydrate.I-AFP ingelinye lamaprotheni athile aqondene nombungu futhi iyiphrotheni ye-serum ehamba phambili ekuqaleni kwempilo yombungu womuntu njengenyanga eyodwa, lapho i-albumin ne-transferrin zikhona ngamanani amancane uma kuqhathaniswa.Iqala ukuhlanganiswa ku-h... -
I-Anti-MP-P1Antibody, Igundane I-Monoclonal
Imininingwane yomkhiqizo Ulwazi Olujwayelekile I-Mycoplasma pneumoniae iyi-genome encishisiwe ye-pathogen kanye ne-causative agent ye-pneumonia etholwe ngumphakathi.Ukuze ithelele amangqamuzana aphethe, i-Mycoplasma pneumoniae inamathela ku-epithelium eyi-ciliated emgudwini wokuphefumula, odinga ukusebenzisana kwamaprotheni amaningana ahlanganisa i-P1, i-P30, i-P116.I-P1 ama-adhesin angaphezulu aphezulu e-M. pneumoniae, abonakala ebandakanyeka ngokuqondile ekubopheni ama-receptor.Lena i-adhesin eyaziwa nangokuthi i-immunogenic enamandla ...
